ASMT Antibody

Product Specifications

Background

ASMT belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland.

NCBI Gene ID

438

Swiss Prot

P46597

Accession Number

P46597

Host

Rabbit

Reactivity

Human

Immunogen

This ASMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the Central region of human ASMT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Symbol

ASMT

NCBI Official Name

Acetylserotonin O-methyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Melke, J., et al. Mol. Psychiatry 13 (1) :90-98 (2008)

Background Reference 02

Toma, C., et al. Mol. Psychiatry 12 (11) :977-979 (2007)

Background Reference 03

Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

Background Reference 04

Itoh, M.T., et al. Horm. Metab. Res. 35 (3) :153-157 (2003)

Other Product Names

Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase, HIOMT, ASMT

Tested Applications

WB, IHC-P, Flow

Protein ID

1170276

Physical Properties

Liquid

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