RNASEH2B Antibody

Product Specifications

Background

RNASEH2B is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. RNASEH2B is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication.

NCBI Gene ID

79621

Swiss Prot

Q5TBB1

Accession Number

Q5TBB1

Host

Rabbit

Reactivity

Human

Immunogen

This RNASEH2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the Central region of human RNASEH2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

RNASEH2B

NCBI Official Name

Ribonuclease H2 subunit B

NCBI Organism

Homo sapiens

Background Reference 01

Crozat, K., et al. Immunol. Rev. 227 (1) :129-149 (2009)

Background Reference 02

Chon, H., et al. Nucleic Acids Res. 37 (1) :96-110 (2009)

Background Reference 03

Crow, Y.J., et al. Dev Med Child Neurol 50 (6) :410-416 (2008)

Other Product Names

Ribonuclease H2 subunit B, RNase H2 subunit B, Aicardi-Goutieres syndrome 2 protein, AGS2, Deleted in lymphocytic leukemia 8, Ribonuclease HI subunit B, RNASEH2B, DLEU8