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CD138 Antibody

Product Specifications

Background

CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.

NCBI Gene ID

6382

Swiss Prot

P18827

Accession Number

P18827

Host

Rabbit

Reactivity

Human

Immunogen

This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human CD138.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SDC1

NCBI Official Name

Syndecan-1

NCBI Organism

Homo sapiens

Background Reference 01

Rikova, K., et.al., Cell 131 (6), 1190-1203 (2007)

Background Reference 02

Endo, K., et.al., J. Biol. Chem. 278 (42), 40764-40770 (2003)

Other Product Names

Syndecan-1, SYND1, CD138, SDC1, SDC

Tested Applications

WB

Protein ID

229463011

Physical Properties

Liquid

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