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GOT1 Antibody

Product Specifications

Background

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

NCBI Gene ID

2805

Swiss Prot

P17174

Accession Number

P17174

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GOT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-381 amino acids from the C-terminal region of human GOT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-617

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Symbol

GOT1

NCBI Official Name

Aspartate aminotransferase, cytoplasmic

NCBI Organism

Homo sapiens

Background Reference 01

Franke, A., et al. Nat. Genet. 42 (4) :292-294 (2010)

Background Reference 02

Barrett, J.C., et al. Nat. Genet. 41 (12) :1330-1334 (2009)

Background Reference 03

Campos, J., et al. Eur. J. Intern. Med. 20 (3), E53-E56 (2009)

Other Product Names

Aspartate aminotransferase, cytoplasmic, cAspAT, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, cCAT, Glutamate oxaloacetate transaminase 1, Transaminase A, GOT1

Tested Applications

WB, IHC-P, Flow

Protein ID

5902703

Physical Properties

Liquid

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