APRT Antibody
Product Specifications
Background
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP) . It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
NCBI Gene ID
353
Swiss Prot
P07741
Accession Number
P07741
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
APRT
NCBI Official Name
Adenine phosphoribosyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Silva, C.H., et. al., J. Biomol. Struct. Dyn. 25 (6), 589-597 (2008)
Background Reference 02
Di Pietro, V., et. al., Clin. Biochem. 40 (1-2), 73-80 (2007)
Other Product Names
Adenine phosphoribosyltransferase, APRT, APRT
Tested Applications
WB, IHC-P
Protein ID
114074
Physical Properties
Liquid
Curated Selection
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