DCC1 Antibody

Product Specifications

Background

CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]) .

NCBI Gene ID

79075

Swiss Prot

Q9BVC3

Accession Number

Q9BVC3

Host

Rabbit

Reactivity

Human

Immunogen

This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human DCC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DSCC1

NCBI Official Name

Sister chromatid cohesion protein DCC1

NCBI Organism

Homo sapiens

Background Reference 01

Murakami, T., et al. J. Biol. Chem. 285 (45) :34608-34615 (2010)

Background Reference 02

Terret, M.E., et al. Nature 462 (7270) :231-234 (2009)

Background Reference 03

Watrin, E., et al. Curr. Biol. 16 (9) :863-874 (2006)

Background Reference 04

Bermudez, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (18) :10237-10242 (2003)

Other Product Names

Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1

Tested Applications

Protein ID

167012058

Physical Properties

Liquid

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