CDA Antibody
Product Specifications
Background
CDA forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in the CDA gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
NCBI Gene ID
978
Swiss Prot
P32320
Accession Number
P32320
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-83 amino acids from the Central region of human CDA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDA
NCBI Official Name
Cytidine deaminase
NCBI Organism
Homo sapiens
Background Reference 01
Laliberte J., Momparler R.L.Cancer Res. 54:5401-5407 (1994)
Background Reference 02
Demontis S., Terao M.Biochim. Biophys. Acta 1443:323-333 (1998)
Background Reference 03
Kuhn K., Bertling W.M., Emmrich F.Biochem. Biophys. Res. Commun. 190:1-7 (1993)
Other Product Names
Cytidine deaminase, Cytidine aminohydrolase, CDA, CDD
Tested Applications
WB
Protein ID
1705718
Physical Properties
Liquid
Curated Selection
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