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EBP1 Antibody

Product Specifications

Background

PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.

NCBI Gene ID

5036

Swiss Prot

Q9UQ80

Accession Number

Q9UQ80

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human EBP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-549

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Symbol

PA2G4

NCBI Official Name

Proliferation-associated protein 2G4

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, Y., Mol. Cancer Ther. (10), 3176-3186 (2008)

Background Reference 02

Zhang, Y., Cancer Lett. 265 (2), 298-306 (2008)

Background Reference 03

Okada, M., J. Biol. Chem. 282 (50), 36744-36754 (2007)

Other Product Names

Proliferation-associated protein 2G4, Cell cycle protein p38-2G4 homolog, hG4-1, ErbB3-binding protein 1, PA2G4, EBP1

Tested Applications

WB, IHC-P, Flow

Protein ID

13632817

Physical Properties

Liquid

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