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KRT19 Antibody

Product Specifications

Background

KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

NCBI Gene ID

3880

Swiss Prot

P08727

Accession Number

P08727

Host

Rabbit

Reactivity

Human

Immunogen

This KRT19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human KRT19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Symbol

KRT19

NCBI Official Name

Keratin, type I cytoskeletal 19

NCBI Organism

Homo sapiens

Background Reference 01

Bonzanini, M., Acta Cytol. 52 (5), 541-548 (2008)

Background Reference 02

Yang, X.R., Clin. Cancer Res. 14 (12), 3850-3859 (2008)

Background Reference 03

Maurer, J., PLoS ONE (10), E3451 (2008)

Other Product Names

Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19

Tested Applications

WB, IHC-P

Protein ID

311033484

Physical Properties

Liquid

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