PPAP2C Antibody

Product Specifications

Background

PPAP2C is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B) . All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity.

NCBI Gene ID

8612

Swiss Prot

O43688

Accession Number

O43688

Host

Rabbit

Reactivity

Human

Immunogen

This PPAP2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the C-terminal region of human PPAP2C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Symbol

PPAP2C

NCBI Official Name

Lipid phosphate phosphohydrolase 2

NCBI Organism

Homo sapiens

Background Reference 01

Long, J.S., Biochem. J. 411 (2), 371-377 (2008)

Background Reference 02

Morris, K.E., J. Biol. Chem. 281 (14), 9297-9306 (2006)

Background Reference 03

Nanjundan, M., Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1), L1-L23 (2003)

Background Reference 04

Zhang, N., Genesis 27 (4), 137-140 (2000)

Other Product Names

Lipid phosphate phosphohydrolase 2, PAP2-gamma, PAP2-G, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, PAP-2c, PAP2c, PPAP2C, LPP2