M6PR Antibody

Product Specifications

Background

The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

NCBI Gene ID

4074

Swiss Prot

P20645

Accession Number

P20645

Host

Rabbit

Reactivity

Human

Immunogen

This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human M6PR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

M6PR

NCBI Official Name

Cation-dependent mannose-6-phosphate receptor

NCBI Organism

Homo sapiens

Background Reference 01

Bosker, F.J., et al. Mol. Psychiatry (2010) In press :

Background Reference 02

Op den Brouw, M.L., et al. Virology 393 (1) :84-90 (2009)

Background Reference 03

Schimanski, L.M., et al. Blood Cells Mol. Dis. 43 (2) :180-193 (2009)

Background Reference 04

Rodriguez-Gabin, A.G., et al. Exp. Cell Res. 315 (13) :2215-2230 (2009)

Other Product Names

Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, M6PR, MPR46, MPRD

Tested Applications

WB, IF, Flow

Protein ID

127293

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

H0372 96 Tests

Serine/threonine-protein Kinase TNNI3K (TNNI3K) Mouse ELISA Kit

Ask

View Details

MBS5811335 Inquire

Naboctate HCl

Ask

View Details

NBP3-20763APC 0.1 mL

Mouse Monoclonal CD5 Antibody (rC5/6976) [Allophycocyanin]

Ask

View Details

bs-9093R-RBITC 100 µL

AIM1L Polyclonal Antibody, RBITC Conjugated

Ask

View Details

CPA5177-01 30 µL

Anti-Cytochrome P450 7B1 Antibody

Ask

View Details

CPA5177-02 50 μL

Anti-Cytochrome P450 7B1 Antibody

Ask

View Details