GPC4 Antibody
Product Specifications
Background
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
NCBI Gene ID
2239
Swiss Prot
O75487
Accession Number
O75487
Host
Rabbit
Reactivity
Human
Immunogen
This GPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human GPC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GPC4
NCBI Official Name
Glypican-4
NCBI Organism
Homo sapiens
Background Reference 01
Karumanchi, S.A., Mol. Cell (4), 811-822 (2001)
Background Reference 02
Hagihara, K., Dev. Dyn. 219 (3), 353-367 (2000)
Background Reference 03
Veugelers, M., Hum. Mol. Genet. (9), 1321-1328 (2000)
Background Reference 04
Veugelers, M., Genomics 53 (1), 1-11 (1998)
Other Product Names
Glypican-4, K-glypican, Secreted glypican-4, GPC4
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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