AASS Antibody
Product Specifications
Background
AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.
NCBI Gene ID
10157
Swiss Prot
Q9UDR5
Accession Number
Q9UDR5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of human AASS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Symbol
AASS
NCBI Official Name
Alpha-aminoadipic semialdehyde synthase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Sacksteder, K.A., Am. J. Hum. Genet. 66 (6), 1736-1743 (2000)
Other Product Names
Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS
Tested Applications
WB, IHC-P
Protein ID
46396032
Physical Properties
Liquid
Curated Selection
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