TRF Antibody

Product Specifications

Background

TERF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.

NCBI Gene ID

7013

Swiss Prot

P54274

Accession Number

P54274

Host

Rabbit

Reactivity

Human

Immunogen

This TRF (TERF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human TRF (TERF1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Hamster

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TERF1

NCBI Official Name

Telomeric repeat-binding factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Kim, M.K., J. Biol. Chem. 283 (20), 14144-14152 (2008)

Background Reference 02

Etheridge, K.T., J. Biol. Chem. 283 (11), 6935-6941 (2008)

Background Reference 03

Muramatsu, Y., Exp. Cell Res. 314 (5), 1115-1124 (2008)

Other Product Names

Telomeric repeat-binding factor 1, NIMA-interacting protein 2, TTAGGG repeat-binding factor 1, Telomeric protein Pin2/TRF1, TERF1, PIN2, TRBF1, TRF, TRF1