LGR5 Antibody

Product Specifications

Background

LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues.

NCBI Gene ID

8549

Swiss Prot

O75473

Accession Number

O75473

Host

Rabbit

Reactivity

Human

Immunogen

This LGR5 (GPR49) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-473 amino acids from the Central region of human LGR5 (GPR49) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Growth Factors

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

100 kDa

Fragment

Rabbit Ig

Symbol

LGR5

NCBI Official Name

Leucine-rich repeat-containing G-protein coupled receptor 5

NCBI Organism

Homo sapiens

Background Reference 01

Barker, N., Nature 449 (7165), 1003-1007 (2007) McClanahan, T., Cancer Biol. Ther. (4), 419-426 (2006) Yamamoto, Y., Hepatology 37 (3), 528-533 (2003) Hsu, S.Y., Mol. Endocrinol. 14 (8), 1257-1271 (2000)

Other Product Names

Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, LGR5, GPR49, GPR67