PHB1 Antibody
Product Specifications
Background
Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.
NCBI Gene ID
5245
Swiss Prot
P35232
Accession Number
P35232
Host
Rabbit
Reactivity
Human
Immunogen
This PHB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human PHB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PHB
NCBI Official Name
Prohibitin
NCBI Organism
Homo sapiens
Background Reference 01
Gregory-Bass, R.C., Int. J. Cancer 122 (9), 1923-1930 (2008)
Background Reference 02
Ross, J.A., J. Biol. Chem. 283 (8), 4699-4713 (2008)
Background Reference 03
White, J.J., Genomics 11 (1), 228-230 (1991)
Other Product Names
Prohibitin, PHB
Tested Applications
WB
Protein ID
464371
Physical Properties
Liquid
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