SMC2 Antibody
Product Specifications
Background
SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
NCBI Gene ID
10592
Swiss Prot
O95347
Accession Number
O95347
Host
Rabbit
Reactivity
Human
Immunogen
This SMC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1166-1197 amino acids from the C-terminal region of human SMC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
136 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SMC2
NCBI Official Name
Structural maintenance of chromosomes protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Schmiesing, J.A., Proc. Natl. Acad. Sci. U.S.A. 95 (22), 12906-12911 (1998)
Background Reference 02
Ham, M.F., Cancer Sci. 98 (7), 1041-1047 (2007)
Other Product Names
Structural maintenance of chromosomes protein 2, SMC protein 2, SMC-2, Chromosome-associated protein E, hCAP-E, XCAP-E homolog, SMC2, CAPE, SMC2L1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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