PAD4 Antibody

Product Specifications

Background

PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.

NCBI Gene ID

23569

Swiss Prot

Q9UM07

Accession Number

Q9UM07

Host

Rabbit

Reactivity

Human

Immunogen

This PAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the C-terminal region of human PAD4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

74 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PADI4

NCBI Official Name

Protein-arginine deiminase type-4

NCBI Organism

Homo sapiens

Background Reference 01

Nakayama-Hamada, M., et al., Biochem. Biophys. Res. Commun. 327 (1) :192-200 (2005) .

Background Reference 02

Wang, Y., et al., Science 306 (5694) :279-283 (2004) .

Background Reference 03

Arita, K., et al., Arthritis Rheum. 11 (8) :777-783 (2004) .

Background Reference 04

Barton, A., et al., Arthritis Rheum. 50 (4) :1117-1121 (2004) .

Other Product Names

Protein-arginine deiminase type-4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, PADI4, PADI5, PDI5

Tested Applications

Protein ID

296439260

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx270142-01 50 Tests

Endoglin / CD105 (ENG) Antibody

Ask

View Details

abx270142-02 100 Tests

Endoglin / CD105 (ENG) Antibody

Ask

View Details

abx270142-03 200 Tests

Endoglin / CD105 (ENG) Antibody

Ask

View Details

abx270142-04 500 Tests

Endoglin / CD105 (ENG) Antibody

Ask

View Details

MBS1424178-01 0.5 mg (E-Coli)

Recombinant Rat Cell adhesion molecule 3 (Cadm3), partial

Ask

View Details

MBS1424178-02 0.05 mg (Baculovirus)

Recombinant Rat Cell adhesion molecule 3 (Cadm3), partial

Ask

View Details