NMT2 Antibody

Product Specifications

Background

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.

NCBI Gene ID

9397

Swiss Prot

O60551

Accession Number

O60551

Host

Rabbit

Reactivity

Human

Immunogen

This NMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human NMT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

57 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NMT2

NCBI Official Name

Glycylpeptide N-tetradecanoyltransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Lindwasser, O.W., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (20) :13037-13042 (2002) .

Background Reference 02

Kolluri, S.K., et al., Cancer Res. 61 (23) :8534-8539 (2001) .

Background Reference 03

Shiraishi, T., et al., Biochem. Biophys. Res. Commun. 282 (5) :1201-1205 (2001) .

Background Reference 04

Ono, A., et al., J. Virol. 73 (5) :4136-4144 (1999) .

Other Product Names

Glycylpeptide N-tetradecanoyltransferase 2, Myristoyl-CoA:protein N-myristoyltransferase 2, NMT 2, Peptide N-myristoyltransferase 2, Type II N-myristoyltransferase, NMT2