RAGE Antibody

Product Specifications

Background

This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.

NCBI Gene ID

177

Swiss Prot

Q15109

Accession Number

Q15109

Host

Rabbit

Reactivity

Human

Immunogen

This RAGE (AGER) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-378 amino acids from the C-terminal region of human RAGE (AGER) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

AGER

NCBI Official Name

Advanced glycosylation end product-specific receptor

NCBI Organism

Homo sapiens

Background Reference 01

Schlueter, C., et al., Biochim. Biophys. Acta 1630 (1) :1-6 (2003) .

Background Reference 02

Shanmugam, N., et al., J. Biol. Chem. 278 (37) :34834-34844 (2003) .

Background Reference 03

Kuniyasu, H., et al., Oncol. Rep. 10 (2) :445-448 (2003) .

Background Reference 04

Hsieh, H.L., et al., Biochem. Biophys. Res. Commun. 307 (2) :375-381 (2003) .

Other Product Names

Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE

Tested Applications

WB, IHC-P

Protein ID

2497317

Physical Properties

Liquid

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