PLCB3 Antibody

Product Specifications

Background

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

NCBI Gene ID

5331

Swiss Prot

Q01970

Accession Number

Q01970

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

This PLCB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from human PLCB3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

139 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PLCB3

NCBI Official Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

NCBI Organism

Homo sapiens

Background Reference 01

Mazuruk K., et al.Biochem. Biophys. Res. Commun. 212:190-195 (1995) .

Background Reference 02

Lagercrantz J., et al.Genomics 26:467-472 (1995) .

Background Reference 03

Taylor T.D., et al.Nature 440:497-500 (2006) .

Background Reference 04

Mural R.J., et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

Other Product Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, 3.1.4.11, Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3, PLCB3