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HEXIM2 Antibody

Product Specifications

Background

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

NCBI Gene ID

124790

Swiss Prot

Q96MH2

Accession Number

Q96MH2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This HEXIM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-269 amino acids from of human HEXIM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

32 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:8000

Symbol

HEXIM2

NCBI Official Name

Protein HEXIM2

NCBI Organism

Homo sapiens

Background Reference 01

Petroziello J., et al.Oncogene 23:7734-7745 (2004) .

Background Reference 02

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 03

Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Background Reference 04

Byers S.A., et al.J. Biol. Chem. 280:16360-16367 (2005) .

Other Product Names

Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2, HEXIM2

Tested Applications

WB

Protein ID

74732374

Physical Properties

Liquid

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