MAN1A2 Antibody

Product Specifications

Background

Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man (9) GlcNAc (2) to produce Man (5) GlcNAc (2) .

NCBI Gene ID

10905

Swiss Prot

O60476

Accession Number

O60476

Host

Rabbit

Reactivity

Human

Immunogen

This MAN1A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 342-373 amino acids from the Central region of human MAN1A2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

MAN1A2

NCBI Official Name

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

NCBI Organism

Homo sapiens

Background Reference 01

Tremblay L.O., et al.Glycobiology 8:585-595 (1998) .

Background Reference 02

Gregory S.G., et al.Nature 441:315-321 (2006) .

Background Reference 03

Bienvenut W.V., et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131 (2012) .

Background Reference 04

Van Damme P., et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454 (2012) .

Other Product Names

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB, 3.2.1.113, Mannosidase alpha class 1A member 2, Processing alpha-1,2-mannosidase IB, Alpha-1,2-mannosidase IB, MAN1A2, MAN1B