LLGL2 Antibody
Product Specifications
Background
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
NCBI Gene ID
3993
Swiss Prot
Q6P1M3
Accession Number
Q6P1M3
Host
Rabbit
Reactivity
Human
Immunogen
This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-973 amino acids from the C-terminal region of human LLGL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
113 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LLGL2
NCBI Official Name
Lethal (2) giant larvae protein homolog 2
NCBI Organism
Homo sapiens
Background Reference 01
Yasumi, M., et al., J. Biol. Chem. 280 (8) :6761-6765 (2005) . Katoh, M., et al., Int. J. Oncol. 24 (3) :737-742 (2004) .
Other Product Names
Lethal (2) giant larvae protein homolog 2, HGL, LLGL2
Tested Applications
WB
Protein ID
93204600
Physical Properties
Liquid
Curated Selection
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