EFS Antibody
Product Specifications
Background
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity) .
NCBI Gene ID
10278
Swiss Prot
O43281
Accession Number
O43281
Host
Rabbit
Reactivity
Human
Immunogen
This EFS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-399 amino acids from the Central region of human EFS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000-1:2000
Symbol
EFS
NCBI Official Name
Embryonal Fyn-associated substrate
NCBI Organism
Homo sapiens
Background Reference 01
Ishino M., et al.Oncogene 15:1741-1745 (1997) .
Background Reference 02
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Background Reference 03
Heilig R., et al.Nature 421:601-607 (2003) .
Background Reference 04
Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Other Product Names
Embryonal Fyn-associated substrate, hEFS, Cas scaffolding protein family member 3, EFS, CASS3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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