DNASE1L2 Antibody

Product Specifications

Background

Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.

NCBI Gene ID

1775

Swiss Prot

Q92874

Accession Number

Q92874

Host

Rabbit

Reactivity

Human

Immunogen

This DNASE1L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 199-229 amino acids from human DNASE1L2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

DNASE1L2

NCBI Official Name

Deoxyribonuclease-1-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Rodriguez A.M., et al.Genomics 42:507-513 (1997) .

Background Reference 02

Shiokawa D., et al.Genomics 84:95-105 (2004) .

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Martin J., et al.Nature 432:988-994 (2004) .

Other Product Names

Deoxyribonuclease-1-like 2, 3.1.21.-, DNase I homolog protein DHP1, Deoxyribonuclease I-like 2, DNase I-like 2, DNASE1L2, DHP1, DNAS1L2

Tested Applications

Protein ID

2494172

Physical Properties

Liquid

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