GDF3 Antibody
Product Specifications
Background
GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.
NCBI Gene ID
9573
Swiss Prot
Q9NR23
Accession Number
Q9NR23
Host
Rabbit
Reactivity
Human
Immunogen
This GDF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of human GDF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
GDF3
NCBI Official Name
Growth/differentiation factor 3
NCBI Organism
Homo sapiens
Background Reference 01
Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .
Background Reference 02
Ducy, P., et al., Kidney Int. 57 (6) :2207-2214 (2000) .
Background Reference 03
Caricasole, A.A., et al., Oncogene 16 (1) :95-103 (1998) .
Other Product Names
Growth/differentiation factor 3, GDF-3, GDF3
Tested Applications
WB, IHC-P
Protein ID
46397885
Physical Properties
Liquid
Curated Selection
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