GDF10 Antibody

Product Specifications

Background

GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.

NCBI Gene ID

2662

Swiss Prot

P55107

Accession Number

P55107

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GDF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-344 amino acids from the Central region of human GDF10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

GDF10

NCBI Official Name

Bone morphogenetic protein 3B

NCBI Organism

Homo sapiens

Background Reference 01

Ducy, P., et al., Kidney Int. 57 (6) :2207-2214 (2000) .

Background Reference 02

Hino, J., et al., Biochem. Biophys. Res. Commun. 223 (2) :304-310 (1996) .

Background Reference 03

Cunningham, N.S., et al., Growth Factors 12 (2) :99-109 (1995) .

Other Product Names

Bone morphogenetic protein 3B, BMP-3B, Bone-inducing protein, BIP, Growth/differentiation factor 10, GDF-10, GDF10, BMP3B

Tested Applications

WB, Flow

Protein ID

1705471

Physical Properties

Liquid

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