REG3A Antibody

Product Specifications

Background

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.

NCBI Gene ID

5068

Swiss Prot

Q06141

Accession Number

Q06141

Host

Rabbit

Reactivity

Human

Immunogen

This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Symbol

REG3A

NCBI Official Name

Regenerating islet-derived protein 3-alpha

NCBI Organism

Homo sapiens

Background Reference 01

Itoh T., et al.Biochim. Biophys. Acta 1172:184-186 (1993) .

Background Reference 02

Orelle B., et al.J. Clin. Invest. 90:2284-2291 (1992) .

Background Reference 03

Lasserre C., et al.Cancer Res. 52:5089-5095 (1992) .

Background Reference 04

Dusetti N.J., et al.Genomics 19:108-114 (1994) .

Other Product Names

Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1