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C1QA Antibody

Product Specifications

Background

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca (2+) -dependent C1r (2) C1s (2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

NCBI Gene ID

712

Swiss Prot

P02745

Accession Number

P02745

Host

Rabbit

Reactivity

Human

Immunogen

This C1QA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 89-103 amino acids from the Central region of human C1QA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-016

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

C1QA

NCBI Official Name

Complement C1q subcomponent subunit A

NCBI Organism

Homo sapiens

Background Reference 01

Sellar G.C., et al.Biochem. J. 274:481-490 (1991) .

Background Reference 02

Wan T., et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Gregory S.G., et al.Nature 441:315-321 (2006) .

Other Product Names

Complement C1q subcomponent subunit A, C1QA

Tested Applications

WB

Protein ID

399138

Physical Properties

Liquid

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