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JAM3 Antibody

Product Specifications

Background

Participates in cell-cell adhesion. It is a counter- receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) . The soluble form is a mediator of angiogenesis.

NCBI Gene ID

83700

Swiss Prot

Q9BX67

Accession Number

Q9BX67

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This JAM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 261-295 amino acids from the C-terminal region of human JAM3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

JAM3

NCBI Official Name

Junctional adhesion molecule C

NCBI Organism

Homo sapiens

Background Reference 01

Arrate M.P., et al.J. Biol. Chem. 276:45826-45832 (2001) .

Background Reference 02

Aurrand-Lions M.A., et al.Blood 98:3699-3707 (2001) .

Background Reference 03

Santoso S., et al.J. Exp. Med. 196:679-691 (2002) .

Background Reference 04

Phillips H.M., et al.Genomics 79:475-478 (2002) .

Other Product Names

Junctional adhesion molecule C, JAM-C, JAM-2, Junctional adhesion molecule 3, JAM-3, JAM3

Tested Applications

WB

Protein ID

51701611

Physical Properties

Liquid

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