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SDHA Antibody

Product Specifications

Background

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) . Can act as a tumor suppressor.

NCBI Gene ID

6389

Swiss Prot

P31040

Accession Number

P31040

Host

Rabbit

Reactivity

Human

Immunogen

This SDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-605 amino acids from the C-terminal region of human SDHA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Xenopus, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-990

Calculated Molecular Weight

73 kDa

Fragment

Rabbit Ig

Symbol

SDHA

NCBI Official Name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Hirawake H., et al. J. Biochem. 116:221-227 (1994) .

Background Reference 02

Morris A.A.M., et al. Biochim. Biophys. Acta 1185:125-128 (1994) .

Background Reference 03

Parfait B., et al. Hum. Genet. 106:236-243 (2000) .

Background Reference 04

Ota T., et al. Nat. Genet. 36:40-45 (2004) .

Other Product Names

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF

Tested Applications

WB, IHC-P

Protein ID

1169337

Physical Properties

Liquid

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