SEC31A Antibody

Product Specifications

Background

The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER) . This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].

NCBI Gene ID

22872

Swiss Prot

O94979

Accession Number

O94979

Host

Rabbit

Reactivity

Mouse

Immunogen

This SEC31A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the Central region of human SEC31A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

133 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SEC31A

NCBI Official Name

Protein transport protein Sec31A

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Townley, A.K., et al. J. Cell. Sci. 121 (PT 18), 3025-3034 (2008) :

Background Reference 03

Stagg, S.M., et al. Cell 134 (3) :474-484 (2008)

Background Reference 04

Shibata, H., et al. J. Biol. Chem. 283 (15) :9623-9632 (2008)

Other Product Names

Protein transport protein Sec31A, ABP125, ABP130, SEC31-like protein 1, SEC31-related protein A, Web1-like protein, SEC31A, KIAA0905, SEC31L1

Tested Applications

Physical Properties

Liquid

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