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GLUD2 Antibody

Product Specifications

Background

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

NCBI Gene ID

2747

Swiss Prot

P49448

Accession Number

P49448

Host

Rabbit

Reactivity

Human

Immunogen

This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GLUD2

NCBI Official Name

Glutamate dehydrogenase 2, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Spanaki, C., et al. J. Biol. Chem. 285 (22) :16748-16756 (2010)

Background Reference 02

Plaitakis, A., et al. Eur. J. Hum. Genet. 18 (3) :336-341 (2010)

Background Reference 03

Zaganas, I., et al. Neurochem. Int. 55 (1-3), 52-63 (2009) :

Background Reference 04

Mastorodemos, V., et al. Biochem. Cell Biol. 87 (3) :505-516 (2009)

Other Product Names

Glutamate dehydrogenase 2, mitochondrial, GDH 2, GLUD2, GLUDP1

Tested Applications

WB

Protein ID

13432152

Physical Properties

Liquid

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