CHRNB4 Antibody

Product Specifications

Background

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

NCBI Gene ID

1143

Swiss Prot

P30926

Accession Number

P30926

Host

Rabbit

Reactivity

Human

Immunogen

This CHRNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CHRNB4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CHRNB4

NCBI Official Name

Neuronal acetylcholine receptor subunit beta-4

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, H., et al. Neuropsychopharmacology 35 (11) :2211-2224 (2010)

Background Reference 02

Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)

Background Reference 03

Hansen, H.M., et al. Hum. Mol. Genet. 19 (18) :3652-3661 (2010)

Background Reference 04

Amos, C.I., et al. J. Natl. Cancer Inst. 102 (15) :1199-1205 (2010)

Other Product Names

Neuronal acetylcholine receptor subunit beta-4, CHRNB4

Tested Applications

Protein ID

2506129

Physical Properties

Liquid

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