HPS5 Antibody

Product Specifications

Background

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

NCBI Gene ID

11234

Swiss Prot

Q9UPZ3

Accession Number

Q9UPZ3

Host

Rabbit

Reactivity

Human

Immunogen

This HPS5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the N-terminal region of human HPS5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

127 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HPS5

NCBI Official Name

Hermansky-Pudlak syndrome 5 protein

NCBI Organism

Homo sapiens

Background Reference 01

Helip-Wooley, A., et al. J. Invest. Dermatol. 127 (6) :1471-1478 (2007)

Background Reference 02

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 03

Huizing, M., et al. Platelets 18 (2) :150-157 (2007)

Background Reference 04

Huizing, M., et al. Traffic 5 (9) :711-722 (2004)

Other Product Names

Hermansky-Pudlak syndrome 5 protein, Alpha-integrin-binding protein 63, Ruby-eye protein 2 homolog, Ru2, HPS5, AIBP63, KIAA1017

Tested Applications

Protein ID

29429222

Physical Properties

Liquid

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