SYNJ2 Antibody
Product Specifications
Background
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
8871
Swiss Prot
O15056
Accession Number
O15056
Host
Rabbit
Reactivity
Human
Immunogen
This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
166 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SYNJ2
NCBI Official Name
Synaptojanin-2
NCBI Organism
Homo sapiens
Background Reference 01
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 02
Ieguchi, K., et al. J. Biol. Chem. 282 (32) :23296-23305 (2007)
Background Reference 03
Rossi, M.R., et al. Cancer Genet. Cytogenet. 161 (2) :97-103 (2005)
Background Reference 04
Chuang, Y.Y., et al. Cancer Res. 64 (22) :8271-8275 (2004)
Other Product Names
Synaptojanin-2, Synaptic inositol 1,5-trisphosphate 5-phosphatase 2, SYNJ2, KIAA0348
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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