JUN Antibody

Product Specifications

Background

JUN is the putative transforming gene of avian sarcoma virus 17. JUN is a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

NCBI Gene ID

3725

Swiss Prot

P05412

Accession Number

P05412

Host

Rabbit

Reactivity

Human

Immunogen

This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human JUN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction, Inflammasomes

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

JUN

NCBI Official Name

Transcription factor AP-1

NCBI Organism

Homo sapiens

Background Reference 01

Song, J.Y., et al. J. Biol. Chem. 285 (12) :9067-9076 (2010)

Background Reference 02

Jiao, X., et al. J. Biol. Chem. 285 (11) :8218-8226 (2010)

Background Reference 03

Carrillo, R.J., et al. J. Mol. Biol. 396 (2) :431-440 (2010)

Background Reference 04

Maritzen, T., et al. J. Biol. Chem. 285 (6) :4074-4086 (2010)

Other Product Names

Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN

Tested Applications

WB, IHC-P, Flow

Protein ID

135298

Physical Properties

Liquid

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