C8B Antibody

Product Specifications

Background

C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.

NCBI Gene ID

732

Swiss Prot

P07358

Accession Number

P07358

Host

Rabbit

Reactivity

Human

Immunogen

This C8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-422 amino acids from the C-terminal region of human C8B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

67 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

C8B

NCBI Official Name

Complement component C8 beta chain

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 02

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 03

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 04

Gancz, D., et al. Mol. Immunol. 47 (2-3), 310-317 (2009) :

Other Product Names

Complement component C8 beta chain, Complement component 8 subunit beta, C8B

Tested Applications

Protein ID

20141201

Physical Properties

Liquid

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