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UGT2B4 Antibody

Product Specifications

Background

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol) . It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

NCBI Gene ID

7363

Swiss Prot

P06133

Accession Number

P06133

Host

Rabbit

Reactivity

Human

Immunogen

This UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UGT2B4

NCBI Official Name

UDP-glucuronosyltransferase 2B4

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Levesque, E., et al. Pharmacogenet. Genomics 20 (3) :195-210 (2010)

Background Reference 03

Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (2) :537-546 (2010)

Background Reference 04

Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :

Other Product Names

UDP-glucuronosyltransferase 2B4, UDPGT 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1, UGT2B4, UGT2B11

Tested Applications

WB

Protein ID

6175083

Physical Properties

Liquid

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