SETD1A Antibody

Product Specifications

Background

SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005 [PubMed 16253997]) . Also see SET1B (MIM 611055) .

NCBI Gene ID

9739

Swiss Prot

O15047

Accession Number

O15047

Host

Rabbit

Reactivity

Human

Immunogen

This SETD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 927-956 amino acids from the Central region of human SETD1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

186 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SETD1A

NCBI Official Name

Histone-lysine N-methyltransferase SETD1A

NCBI Organism

Homo sapiens

Background Reference 01

Wu, M., et al. Mol. Cell. Biol. 28 (24) :7337-7344 (2008)

Background Reference 02

Nguyen, P., et al. Mol. Cell. Biol. 28 (21) :6720-6729 (2008)

Background Reference 03

Ansari, K.I., et al. Biochim. Biophys. Acta 1779 (1) :66-73 (2008)

Background Reference 04

Lee, J.H., et al. Mol. Cell. Biol. 28 (2) :609-618 (2008)

Other Product Names

Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1, SETD1A