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ASTN2 Antibody

Product Specifications

Background

This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus.

NCBI Gene ID

23245

Swiss Prot

O75129

Accession Number

O75129

Host

Rabbit

Reactivity

Mouse

Immunogen

This ASTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the N-terminal region of human ASTN2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

148 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ASTN2

NCBI Official Name

Astrotactin-2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Adkins, D.E., et al. Mol. Psychiatry (2010) In press :

Background Reference 03

Lesch, K.P., et al.Neural Transm 115 (11) :1573-1585 (2008)

Background Reference 04

Vrijenhoek, T., et al. Am. J. Hum. Genet. 83 (4) :504-510 (2008)

Other Product Names

Astrotactin-2, ASTN2, KIAA0634

Tested Applications

WB

Physical Properties

Liquid

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