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TIPIN Antibody

Product Specifications

Background

Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

NCBI Gene ID

54962

Swiss Prot

Q9BVW5

Accession Number

Q9BVW5

Host

Rabbit

Reactivity

Human

Immunogen

This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TIPIN

NCBI Official Name

TIMELESS-interacting protein

NCBI Organism

Homo sapiens

Background Reference 01

Kemp, M.G., et al. J. Biol. Chem. 285 (22) :16562-16571 (2010)

Background Reference 02

Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010) :

Background Reference 03

Utge, S.J., et al. PLoS ONE (2), E9259 (2010) :

Background Reference 04

Unsal-Kacmaz, K., et al. Mol. Cell. Biol. 27 (8) :3131-3142 (2007)

Other Product Names

TIMELESS-interacting protein, TIPIN

Tested Applications

WB

Protein ID

296452932

Physical Properties

Liquid

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