EIF4E2 Antibody

Product Specifications

Background

EIF4E2 is expressed exclusively in the cytoplasm. This protein recognizes and binds the 7 methylguanosine containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

NCBI Gene ID

9470

Swiss Prot

O60573

Accession Number

O60573

Host

Rabbit

Reactivity

Human

Immunogen

This EIF4E2 antibody is generated from rabbits immunized with human EIF4E2 recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Symbol

EIF4E2

NCBI Official Name

Eukaryotic translation initiation factor 4E type 2

NCBI Organism

Homo sapiens

Background Reference 01

Rom, E., et al., J. Biol. Chem. 273 (21) :13104-13109 (1998) .

Background Reference 02

Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (14) :8175-8180 (1998) .

Background Reference 03

Tee, A.R., et al., FEBS Lett. 564 (1-2), 58-62 (2004) () : () .

Other Product Names

Eukaryotic translation initiation factor 4E type 2, eIF-4E type 2, eIF4E type 2, Eukaryotic translation initiation factor 4E homologous protein, Eukaryotic translation initiation factor 4E-like 3, eIF4E-like protein 4E-LP, mRNA cap-binding protein 4EHP, mRNA cap-binding protein type 3, EIF4E2, EIF4EL3