EIF4B Antibody

Product Specifications

Background

EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with EIF4-F and EIF4-A by binding near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. It also promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F

NCBI Gene ID

1975

Swiss Prot

P23588

Accession Number

P23588

Host

Rabbit

Reactivity

Human

Immunogen

This EIF4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from human EIF4B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

69 kDa

Fragment

Rabbit Ig

Symbol

EIF4B

NCBI Official Name

Eukaryotic translation initiation factor 4B

NCBI Organism

Homo sapiens

Background Reference 01

Doepker, R.C., et al., J. Virol. 78 (9) :4684-4699 (2004) .

Background Reference 02

Fleming, K., et al., Biochemistry 42 (30) :8966-8975 (2003) .

Background Reference 03

Milburn, S.C., et al., EMBO J. 9 (9) :2783-2790 (1990) .

Other Product Names

Eukaryotic translation initiation factor 4B, eIF-4B, EIF4B

Tested Applications

WB, IHC-P

Protein ID

205371761

Physical Properties

Liquid

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