CCKAR Antibody

Product Specifications

Background

This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.

NCBI Gene ID

886

Swiss Prot

P32238

Accession Number

P32238

Host

Rabbit

Reactivity

Human

Immunogen

This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCKAR

NCBI Official Name

Cholecystokinin receptor type A

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Cong, P., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G742-G750 (2010) :

Background Reference 03

Tiwari, A.K., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry (2010) In press :

Background Reference 04

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Other Product Names

Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, CCKAR, CCKRA

Tested Applications

Protein ID

416772

Physical Properties

Liquid

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