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VPREB1 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation.

NCBI Gene ID

7441

Swiss Prot

P12018

Accession Number

P12018

Host

Rabbit

Reactivity

Human

Immunogen

This VPREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the Central region of human VPREB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VPREB1

NCBI Official Name

Immunoglobulin iota chain

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 02

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 03

Rossi, B., et al. J. Immunol. 177 (2) :796-803 (2006)

Background Reference 04

Collins, J.E., et al. Genome Biol. (10), R84 (2004) :

Other Product Names

Immunoglobulin iota chain, CD179 antigen-like family member A, Protein VPreB1, V (pre) B protein, VpreB protein, CD179a, VPREB1, VPREB

Tested Applications

WB

Protein ID

9911096

Physical Properties

Liquid

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