Mouse Sin3a Antibody

Product Specifications

Background

Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

NCBI Gene ID

20466

Swiss Prot

Q60520

Accession Number

Q60520

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Human

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.