EIF2C2 Antibody

Product Specifications

Background

EIF2C2 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing.

NCBI Gene ID

239528

Swiss Prot

Q8CJG0

Accession Number

Q8CJG0

Host

Rabbit

Reactivity

Human

Immunogen

This EIF2C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-59 amino acids from the N-terminal region of human EIF2C2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

97 kDa

Fragment

Rabbit Ig

Symbol

Ago2

NCBI Official Name

Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031}

NCBI Organism

Mus musculus

Background Reference 01

Rivas, F.V., et al., Nat Struct Mol Biol 12 (4) :340-349 (2005) .

Background Reference 02

Liu, J., et al., Science 305 (5689) :1437-1441 (2004) .

Background Reference 03

Nelson, P.T., et al., RNA 10 (3) :387-394 (2004) .

Background Reference 04

Sasaki, T., et al., Genomics 82 (3) :323-330 (2003) .

Other Product Names

Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031}, Argonaute2 {ECO:0000255|HAMAP-Rule:MF_03031}, mAgo2, 3126n2 {ECO:0000255|HAMAP-Rule:MF_03031}, Argonaute RISC catalytic component 2, Eukaryotic translation initiation factor 2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, eIF-2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, eIF2C 2 {ECO:0000255|HAMAP-Rule:MF_03031}, Piwi/argonaute family protein meIF2C2, Protein slicer {ECO:0000255|HAMAP-Rule:MF_03031}, Ago2, Eif2c2, Kiaa4215