FERMT2 Antibody

Product Specifications

Background

FERMT2 participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites.

NCBI Gene ID

10979

Swiss Prot

Q96AC1

Accession Number

Q96AC1

Host

Rabbit

Reactivity

Human

Immunogen

This FERMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 641-669 amino acids from the C-terminal region of human FERMT2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FERMT2

NCBI Official Name

Fermitin family homolog 2

NCBI Organism

Homo sapiens

Background Reference 01

An, Z., et al. Int. J. Cancer 127 (9) :1999-2008 (2010) Bledzka, K., et al. J. Biol. Chem. 285 (40) :30370-30374 (2010) Lai-Cheong, J.E., et al. Int. J. Biochem. Cell Biol. 42 (5) :595-603 (2010) Lai-Cheong, J.E., et al. J. Invest. Dermatol. 128 (9) :2156-2165 (2008) Ma, Y.Q., et al. J. Cell Biol. 181 (3) :439-446 (2008)

Other Product Names

Fermitin family homolog 2, Kindlin-2, Mitogen-inducible gene 2 protein, MIG-2, Pleckstrin homology domain-containing family C member 1, PH domain-containing family C member 1, FERMT2, KIND2, MIG2, PLEKHC1